In any clinical practice, patient safety is the highest priority. A crucial aspect of ensuring this safety is the ability to recognize "clinical flags"—warning signs that may indicate a serious underlying condition requiring immediate medical attention or a referral. This article provides a clear and practical framework for practitioners by organizing these warnings into a five-color system. It moves beyond the well-known "red flags" (signs of serious pathology like cancer or infection) to explore other critical categories. The author details yellow flags (psychosocial factors like fear-avoidance beliefs that can impede recovery), blue flags (socio-economic factors like workplace stress), black flags (systemic or occupational obstacles), and orange flags (psychiatric conditions). For each color, the piece offers concrete clinical examples relevant to a TCM or acupuncture practice, explaining what to look for during patient intake and treatment. This system provides a comprehensive and memorable tool for risk assessment and differential diagnosis. It empowers practitioners to know their clinical limitations, make appropriate and timely referrals, and ultimately provide safer, more effective, and more responsible care, solidifying their role as trusted healthcare professionals.